MiniHowTo:

SECIS design

(1) generate sequences compatible with the design constrains in secis.txt
    > ../secisFindSeqs -M 9 -S 30 < secis.txt > sequences_m9_s30

    M ...... maximal number of point mutations
    S ...... minimal protein alignment score

(2) convert sequences file to barriers input file
    > ./to_bar_in.pl sequences_m9_s30 > m9s30.in

(3) call barriers
    > ../../barriers m9s30.bar > m9s30.bar
    > mv tree.ps m9s30.ps

=;)

