pool {snpMatrix} | R Documentation

## Pool test results from several studies or sub-studies

### Description

Given the same set of "score" tests carried out in several studies or in several different sub-samples within a study, this function pools the evidence by summation of the score statistics and score variances. It combines tests produced by `single.snp.tests` or by `snp.lhs.tests` and `snp.rhs.tests`.

### Usage

    pool(..., score = FALSE)

### Arguments

`...` | Objects holding the (extended) test results. These must be of class `snp.tests.single.score` or `snp.tests.glm`
`score` | Is extended score information to be returned in the output object? Relevant only for `snp.tests.single.score` objects

### Details

This function works by recursive calls to the generic function `pool2` which pools the results of two studies.

### Value

An object of same class as the input objects (optionally without the `.score`) extension. Tests are produced for the union of SNPs tested in all the input objects.

### Author(s)

David Clayton david.clayton@cimr.cam.ac.uk

### See Also

`pool2`, `snp.tests.single.score-class`, `snp.tests.glm-class`, `single.snp.tests`, `snp.lhs.tests`, `snp.rhs.tests`

### Examples

    # An artificial example which simply doubles the size of a study
    library(snpMatrix)
    data(testdata)
    sst <- single.snp.tests(snp.data=Autosomes, cc, data=subject.data,
             score=TRUE)
    sst2 <- pool(sst, sst)
    summary(sst2)

[Package snpMatrix version 1.8.0 Index]