ppipred {y2hStat} | R Documentation

## Protein-protein predictions

### Description

The data in `ppipred` are those provided by Liu et al for S. cervisiae protein protein interactions.

### Usage

    data(ppipred)

### Format

A data frame with 20088 observations on the following 3 variables.

`Gene1`
  A vector of the gene names for one interactor.
`Gene2`
  A vector of the gene names for the other interactor.
`Probability`
  A vectror containing the probability they give to the interaction.

### Details

Liu et al discuss a method for estimating protein-protein interactions from existing data, across species. They have provided the data with the following description: “We compute domain-domain interaction probabilities from Y2H protein-protein interactions, and then use these domain-domain interaction probabilities to compute the interaction probability between every pair of proteins. The prediction results with a false positive rate fp=3E-4 and a false negative rate fn=0.85 are listed blow.”

### Source

http://bioinformatics.med.yale.edu/interaction/

### References

Inferring protein-protein interactions through high-throughput interaction data from diverse organisms, Y. Liu, N. Liu and H. Zhao, Bioinformatics, 2005, 21, 3279-3285.

### Examples

    data(ppipred)

[Package y2hStat version 1.2.0 Index]