Package: twilight
Version: 1.4.0
Title: Estimation of local false discovery rate
Author: Stefanie Scheid <stefanie.scheid@molgen.mpg.de>
Description: In a typical microarray setting with gene expression data
        observed under two conditions, the local false discovery rate
        describes the probability that a gene is not differentially
        expressed between the two conditions given its corrresponding
        observed score or p-value level. The resulting curve of
        p-values versus local false discovery rate offers an insight
        into the twilight zone between clear differential and clear
        non-differential gene expression. Package TWILIGHT contains two
        main functions: Function twilight.pval performs a two-condition
        test on differences in means for a given input matrix or
        expression set and computes permutation based p-values.
        Function twilight performs a stochastic downhill search to
        estimate local false discovery rates and effect size
        distributions.
Maintainer: Stefanie Scheid <stefanie.scheid@molgen.mpg.de>
Depends: R (>= 2.1.0), splines (>= 2.2.0), stats (>= 2.2.0)
Suggests: golubEsets (>= 1.0), vsn (>= 1.7.2)
License: GPL version 2.0 or newer
URL: http://compdiag.molgen.mpg.de/software/twilight.shtml
biocViews: Microarray, Statistics, DifferentialExpression,
        MultipleComparisons
Packaged: Thu Oct 13 00:18:19 2005; biocbuild
Built: R 2.2.0; i386-pc-mingw32; 2005-10-13 00:18:23; windows
