AptMidas            package:oneChannelGUI            R Documentation

_G_r_a_p_h_i_c_a_l _i_n_t_e_r_f_a_c_e _t_o _A_P_T _m_i_d_a_s

_D_e_s_c_r_i_p_t_i_o_n:

     This is a graphical interface to the midas program for detection
     of alternative splicing detection implemented in the Affymetrix
     APT tools

_U_s_a_g_e:

     AptMidas()

_D_e_t_a_i_l_s:

_V_a_l_u_e:

_N_o_t_e:

     For more information see Affymetrix Alternative Transcript
     Analysis Methods for Exon Arrays whitepaper. Before using MiDAS is
     strongly recomanded to filter out gene level probe sets with low
     intensity values to avoid searching alternative splicing for probe
     sets which are not expressed. This can be done using  filtering
     method implemented in oneChannelGUI which define a background
     intensity threshold on the basis of the intron exon signals of a
     set of housekeeping genes present in the exon arrays. However it
     is also possible to use a filter based on the dabg p-value
     calculated using Affymetrix APT tools. This function will also
     calculate Splice Index

_A_u_t_h_o_r(_s):

     Raffaele A Calogero

_R_e_f_e_r_e_n_c_e_s:

_S_e_e _A_l_s_o:

     erankProdAltSpl

_E_x_a_m_p_l_e_s:

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