Package: bridge
Title: Bayesian Robust Inference for Differential Gene Expression
Version: 1.8.0
Author: Raphael Gottardo
Description: Test for differentially expressed genes with microarray
        data. This package can be used with both cDNA microarrays or
        Affymetrix chip. The packge fits a robust Bayesian hierarchical
        model for testing for differential expression. Outliers are
        modeled explicitly using a $t$-distribution. The model includes
        an exchangeable prior for the variances which allow different
        variances for the genes but still shrink extreme empirical
        variances. Our model can be used for testing for differentially
        expressed genes among multiple samples, and can distinguish
        between the different possible patterns of differential
        expression when there are three or more samples. Parameter
        estimation is carried out using a novel version of Markov Chain
        Monte Carlo that is appropriate when the model puts mass on
        subspaces of the full parameter space.
Maintainer: Raphael Gottardo <raph@stat.ubc.ca>
Depends: R (>= 1.9.0), rama
License: GPL version 2 or newer
biocViews: Microarray,OneChannel,TwoChannel,DifferentialExpression
Packaged: Wed Apr 25 03:43:57 2007; biocbuild
Built: R 2.5.0; i386-pc-mingw32; 2007-04-25 06:40:44; windows
