hedenfalk               package:qvalue               R Documentation

_G_e_n_e _e_x_p_r_e_s_s_i_o_n _d_a_t_a_s_e_t _f_r_o_m _H_e_d_e_n_f_a_l_k _e_t _a_l. (_2_0_0_1)

_D_e_s_c_r_i_p_t_i_o_n:

     The data come from the breast cancer cDNA microarray experiment of
     Hedenfalk et al. (2001).  In  the original experiment, comparison
     was made between 3,226 genes of two mutation types, BRCA1  (7
     arrays) and BRCA2 (8 arrays).  The data included here are p-values
     obtained from a two- sample t-test analysis on a subset of 3,170
     genes, as described in Storey and Tibshirani (2003).

_U_s_a_g_e:

     data(hedenfalk)

_V_a_l_u_e:

hedenfalk: Vector of 3,170 p-values of tests comparing BRCA1 to BRCA2.

_R_e_f_e_r_e_n_c_e_s:

     Hedenfalk I et al. (2001). Gene expression profiles in hereditary
     breast cancer.  New Engl. Jour. Medicine, 344: 539-548.

     Storey JD and Tibshirani R. (2003). Statistical significance for
     genome-wide  studies. Proceedings of the National Academy of
     Sciences, 100: 9440-9445.

