edesignDR              package:maSigPro              R Documentation

_E_x_p_e_r_i_m_e_n_t_a_l _d_e_s_i_g_n _w_i_t_h _d_i_f_f_e_r_e_n_t _r_e_p_l_i_c_a_t_e_s

_D_e_s_c_r_i_p_t_i_o_n:

     'edesignDR' contains experimental set up of a replicated time
     course microarray experiment where ratas were submitted to 3
     different dosis of a toxic compound. A control and an placebo
     treatments are also present in the experiment.

_U_s_a_g_e:

     data(edesignDR)

_F_o_r_m_a_t:

     A matrix with 54 rows and 7 columns

          rows [1:54] "Array1" "Array2" "Array3" "Array4" ... \newline
          columns [1:7] "Time" "Replicates" "Control" "Placebo" "Low"
          "Medium" "High" 

_D_e_t_a_i_l_s:

     Arrays are given in rows and experiment descriptors are given in
     columns. Row names contain array names. \newline        '"Time"'
     indicates the values that variable Time takes in each
     hybridization. \newline '"Replicates"' is an index indicating
     replicate hyridizations, i.e. hybridizations are numbered, giving
     replicates the same number. \newline '"Control"', '"Placebo"',
     '"Low"', '"Medium"' and '"High"' columns indicate array assigment
     to experimental groups, coding with 1 and 0 whether each array
     belongs to that group or not.

_R_e_f_e_r_e_n_c_e_s:

     Heijne, W.H.M.; Stierum, R.; Slijper, M.; van Bladeren P.J. and
     van Ommen B.(2003). Toxicogenomics of bromobenzene hepatotoxicity:
     a combined transcriptomics and proteomics approach. Biochemical
     Pharmacology 65 857-875.

_E_x_a_m_p_l_e_s:

     data(edesignDR)

