agep {wateRmelon} | R Documentation

## Age Prediction from methylomic expression data

### Description

Predict age of samples using Horvaths Coefficients

### Usage

    agep(betas, coeff=NULL, method=c('horvath','hannum') ,...)

### Arguments

`betas` | Matrix of betas or MethyLumiSet or MethylSet object.
`coeff` | If NULL, will default to Horvaths coefficients. Otherwise can be supplied with vector of own coefficients with an intercept as first element.
`method` | currently either "horvath" or "hannum". If using "hannum" remember to call data(hannumCoef) before analysis and supply coeff with the hannum coefficients, otherwise will default to "horvath".
`...` | To pass to arguments to downstream functions to specify adult.age

### Value

Returns matrix of predicted ages per sample.

### Author(s)

Original Functions: Steve Horvath

wateRmelon Implementation: Leo Schalkwyk, Louis El Khoury

### References

Horvath S: DNA methylation age of human tissues and cell types. Genome Biology 2013, 14:R115

### Examples

    data(melon)
    data(coef)
    agep(melon,coeff=coef)
    # or
    agep(betas(melon),coeff=coef)

[Package wateRmelon version 1.28.0 Index]