SparseDCParams {splatter} | R Documentation

## The SparseDCParams class

### Description

S4 class that holds parameters for the SparseDC simulation.

### Parameters

The SparseDC simulation uses the following parameters:

`nGenes`

  The number of genes to simulate in each condition.

`nCells`

  The number of cells to simulate.

`[seed]`

  Seed to use for generating random numbers.

`markers.n`

  Number of marker genes to simulate for each cluster.

`markers.shared`

  Number of marker genes for each cluster shared between conditions. Must be less than or equal to `markers.n`

.

`[markers.same]`

  Logical. Whether each cluster should have the same set of marker genes.

`clusts.c1`

  Numeric vector of clusters present in condition 1. The number of times a cluster is repeated controls the proportion of cells from that cluster.

`clusts.c2`

  Numeric vector of clusters present in condition 2. The number of times a cluster is repeated controls the proportion of cells from that cluster.

`[mean.lower]`

  Lower bound for cluster gene means.

`[mean.upper]`

  Upper bound for cluster gene means.

The parameters not shown in brackets can be estimated from real data using `sparseDCEstimate`. For details of the SparseDC simulation see `sparseDCSimulate`.

[Package splatter version 1.8.0 Index]