signatureEnrichment {maftools} | R Documentation

## Performs sample stratification based on signature contribution and enrichment analysis.

### Description

Performs k-means clustering to assign signature to samples and performs enrichment analysis.

### Usage

    signatureEnrichment(maf, sig_res, minMut = 5, useCNV = FALSE,
      fn = NULL)

### Arguments

`maf` | an `MAF` object used for signature analysis.
`sig_res` | Signature results from `extractSignatures`
`minMut` | Consider only genes with minimum this number of samples mutated. Default 5.
`useCNV` | whether to include copy number events. Only applicable when MAF is read along with copy number data. Default TRUE if available.
`fn` | basename for output file. Default NULL.

### Value

result list containing p-values

### See Also

`plotEnrichmentResults` `plotCopheneticMetric`

[Package maftools version 2.0.16 Index]