estiExonNBstat {SeqGSEA} | R Documentation

## Calculate NB-statistics quantifying differential splicing for individual exons

### Description

Calculate NB-statistics quantifying differential splicing for individual exons between two groups of samples compared.

### Usage

    estiExonNBstat(RCS)

### Arguments

`RCS` | a ReadCountSet object after running `exonTestability`.

### Value

A ReadCountSet object with the slot `featureData` updated.

### Note

Please run `exonTestability` before you run this function.

### Author(s)

Xi Wang, xi.wang@newcastle.edu.au

### References

Weichen Wang, Zhiyi Qin, Zhixing Feng, Xi Wang and Xuegong Zhang (2013). Identifying differentially spliced genes from two groups of RNA-seq samples. Gene, 518(1):164-170.

### See Also

`exonTestability`, `estiGeneNBstat`

### Examples

    data(RCS_example, package="SeqGSEA")
    RCS_example <- exonTestability(RCS_example, cutoff=5)
    RCS_example <- estiExonNBstat(RCS_example)
    head(fData(RCS_example))

[Package SeqGSEA version 1.24.0 Index]