computeAmax {PharmacoGx} | R Documentation

## Fits dose-response curves to data given by the user and returns the Amax of the fitted curve. Amax: 100 - viability at maximum concentarion (in fitted curve)

### Description

Fits dose-response curves to data given by the user and returns the Amax of the fitted curve. Amax: 100 - viability at maximum concentarion (in fitted curve)

### Usage

    computeAmax(concentration, viability, trunc = TRUE, verbose = FALSE)

### Arguments

`concentration` | [vector] is a vector of drug concentrations.
`viability` | [vector] is a vector whose entries are the viability values observed in the presence of the drug concentrations whose logarithms are in the corresponding entries of the log_conc, expressed as percentages of viability in the absence of any drug.
`trunc` | [logical], if true, causes viability data to be truncated to lie between 0 and 1 before curve-fitting is performed.
`verbose` | [logical] should warnings be printed

### Value

The numerical Amax

### Examples

    dose <- c("0.0025","0.008","0.025","0.08","0.25","0.8","2.53","8")
    viability <- c("108.67","111","102.16","100.27","90","87","74","57")
    computeAmax(dose, viability)

[Package PharmacoGx version 1.14.2 Index]