ssea.analyze.statistic {Mergeomics} | R Documentation

## MSEA statistics for enrichment score

### Description

`ssea.analyze.statistic` estimates the enrichment score based on observed and expected ones.

### Usage

    ssea.analyze.statistic(o, e)

### Arguments

`o` | observed enrichment score
`e` | expected enrichment score

### Value

`score` | estimated enrichment score based on observed and expected scores

### Author(s)

Ville-Petteri Makinen

### References

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Makinen V-P, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. BMC genomics. 2016;17(1):874.

### See Also

`ssea.analyze`

### Examples

    ## O and E the observed and expected counts of positive findings
    ## (enrichment scores) at a given cutoff:
    set.seed(1)
    o <- rnorm(1)
    e <- rnorm(1)
    ## find the final enrichment score from the observed and estimated scores:
    z <- ssea.analyze.statistic(o, e)

[Package Mergeomics version 1.12.0 Index]