GenerateLearningsets {CMA} | R Documentation

## Repeated Divisions into learn- and tets sets

### Description

Due to very small sample sizes, the classical division learnset/testset does not give accurate information about the classification performance. Therefore, several different divisions should be used and aggregated. The implemented methods are discussed in Braga-Neto and Dougherty (2003) and Molinaro et al. (2005) whose terminology is adopted.

This function is usually the basis for all deeper analyses.

### Usage

    GenerateLearningsets(n, y, method = c("LOOCV", "CV", "MCCV", "bootstrap"),
                         fold = NULL, niter = NULL, ntrain = NULL, strat = FALSE)

### Arguments

`n` | The total number of observations in the available data set. May be `missing` if `y` is provided instead.
`y` | A vector of class labels, either `numeric` or a `factor`. Must be given if `strat=TRUE` or `n` is not specified.
`method` | Which kind of scheme should be used to generate divisions into learning sets and test sets ? Can be one of the following: "LOOCV" Leaving-One-Out Cross Validation. "CV" (Ordinary) Cross-Validation. Note that `fold` must as well be specified. "MCCV" Monte-Carlo Cross Validation, i.e. random divisions into learning sets with `ntrain`(s.below) observations and tests sets with `ntrain` observations. "bootstrap" Learning sets are generated by drawing `n` times with replacement from all observations. Those not drawn not all form the test set.
`fold` | Gives the number of CV-groups. Used only when `method="CV"`
`niter` | Number of iterations (s.`details).`
`ntrain` | Number of observations in the learning sets. Used only when `method="MCCV"`.
`strat` | Logical. Should stratified sampling be performed, i.e. the proportion of observations from each class in the learning sets be the same as in the whole data set ? Does not apply for `method = "LOOCV"`.

### Details

- When `method="CV"`, `niter` gives the number of times the whole CV-procedure is repeated. The output matrix has then `fold`x`niter` rows. When `method="MCCV"` or `method="bootstrap"`, `niter` is simply the number of considered learning sets.

- Note that `method="CV",fold=n` is equivalent to `method="LOOCV"`.

### Value

An object of class `learningsets`

### Author(s)

Martin Slawski ms@cs.uni-sb.de

Anne-Laure Boulesteix boulesteix@ibe.med.uni-muenchen.de

Christoph Bernau bernau@ibe.med.uni-muenchen.de

### References

Braga-Neto, U.M., Dougherty, E.R. (2003).

Is cross-validation valid for small-sample microarray classification ?

Bioinformatics, 20(3), 374-380

Molinaro, A.M., Simon, R., Pfeiffer, R.M. (2005).

Prediction error estimation: a comparison of resampling methods.

Bioinformatics, 21(15), 3301-3307

Slawski, M. Daumer, M. Boulesteix, A.-L. (2008) CMA - A comprehensive Bioconductor package for supervised classification with high dimensional data. BMC Bioinformatics 9: 439

### See Also

`learningsets`, `GeneSelection`, `tune`, `classification`

### Examples

    # LOOCV
    loo <- GenerateLearningsets(n=40, method="LOOCV")
    show(loo)
    # five-fold-CV
    CV5 <- GenerateLearningsets(n=40, method="CV", fold=5)
    show(loo)
    # MCCV
    mccv <- GenerateLearningsets(n=40, method = "MCCV", niter=3, ntrain=30)
    show(mccv)
    # Bootstrap
    boot <- GenerateLearningsets(n=40, method="bootstrap", niter=3)
    # stratified five-fold-CV
    set.seed(113)
    classlabels <- sample(1:3, size = 50, replace = TRUE, prob = c(0.3, 0.5, 0.2))
    CV5strat <- GenerateLearningsets(y = classlabels, method="CV", fold=5, strat = TRUE)
    show(CV5strat)

[Package CMA version 1.42.0 Index]