# Targeted Learning with Moderated Statistics for Biomarker Discovery

## Documentation for package ‘biotmle’ version 1.8.0

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

.biotmle | Constructor for class bioTMLE
biomarkertmle | Biomarker Evaluation with Targeted Minimum Loss-Based Estimation of the ATE
biomarkerTMLE_exposure | TMLE procedure using ATE for Biomarker Identication from Exposure
bioTMLE-class | Constructor for class bioTMLE
data.frame_OR_EList-class | S4 class union data.frame_OR_EList
eif | Accessor for Table of Raw Efficient Influence Function Values
heatmap_ic | Heatmap for class biotmle
modtest_ic | Moderated Statistical Tests for Influence Functions
plot.bioTMLE | Plot p-values from moderated statistical tests for class biotmle
rnaseq_ic | Transformation utility for using "voom" with biomarker TMLE procedure
toptable | Accessor for Results Table of Moderated Influence Function Hypothesis Test
volcano_ic | Volcano plot for class biotmle