annotateEntrez {iSEE}R Documentation

Annotation via Entrez database

Description

Annotation facility for displaying additional information on selected genes, based on the data retrieved from the ENTREZ database

Usage

annotateEntrez(se, orgdb, keytype, rowdata_col = NULL)

Arguments

se

An object that is coercible to SingleCellExperiment.

orgdb

An OrgDb object, as a basis for the annotation. Typical values are org.Hs.eg.db for human, org.Mm.eg.db for mouse, and so on. The corresponding package has to be available and loaded before calling this function.

keytype

The keytype that matches the IDs used in the se object. Can be one of keytypes(org.XX.eg.db), typically "SYMBOL", "ENSEMBL", or "ENTREZID".

rowdata_col

A character string specifying which column of rowData(se) contains the keys. Defaults to NULL, which corresponds to having the ids of the features as row names of the se object itself.

Value

A function to be used as the value of the annotFun parameter of iSEE. This function itself returns a HTML tag object with the content extracted from the call, accepting as parameters the se object and the row_index corresponding to the feature of interest.

Examples

library(scRNAseq)
data(allen)
sce <- as(allen, "SingleCellExperiment")

library(org.Mm.eg.db)
myfun <- annotateEntrez(sce, org.Mm.eg.db, keytype="SYMBOL")
## Not run: 
# Requires a working internet connection
myfun(sce, 4242)

## End(Not run)

# to be used when launching the app itself ----

app <- iSEE(sce, annotFun = myfun)
if (interactive()) {
  shiny::runApp(app, port = 1234)
}
[Package iSEE version 1.2.4 Index]