# REMP 0.99.0

* Initial submission to Bioconductor.

# REMP 0.99.14

* Revisions based on the comments to the initial submission.

# REMP 0.99.16

* Package accepted by Bioconductor.

# REMP 0.99.20

* Added trim(REMProduct) functionality to trim predicted CpGs based on quality score (only for Random Forest model).

# REMP 0.99.21

* Improved the robustness of function GRannot() when indicator column "Index" is not provided.
* Fixed the inaccurate RE statistics calculation after function trim() is applied.

# REMP 0.99.22

* Enabled parallel computing in function decodeAnnot(REMProduct).

# REMP 0.99.24

* Vignettes updated
* Fixed bugs for Mac OS and Linux system.

# REMP 0.99.25

* Fixed timeout issue encountered in the build system.

# REMP 1.0.0

* Initial release on Bioconductor.

# REMP 1.0.1

* In groomethy, changed the default KNN imputation direction from "by-column" to "by-row" to avoid out-of-range imputation results. 

# REMP 1.0.4

* Use package 'ranger' to boost computation speed for Random Forest.

# REMP 1.0.7

* Allow random seed for reproducible results using Random Forest.
* Use package 'ranger' to simplfy the code and boost computation speed for Quantile Regression Forest.

# REMP 1.2.1

* Added "rempAggregate" method to "REMProduct" class to enable aggregation algorithm.
* Function name changed: annotation --> rempAnnot, trim --> rempTrim, imp --> rempImp.
* Fixed a bug when using "naive" method.

# REMP 1.2.3

* Allows parallel computing in "rempAggregate" method.
* Added "rempCombine" method to combine two "REMProduct" objects by column.

# REMP 1.2.5

* Added "remprofile" method to get the methylation data profiled in RE.
* Minor bug fixes and improvements.

# REMP 1.4.0

* Version number update (same as REMP 1.2.5). R-3.5.0. Bioconductor 3.7.

# REMP 1.4.1

* Fix bug in grooMethy
* Added parameters to control the behaviors of imputation in "remprofile".