toy_network {cosmosR} | R Documentation

## Toy Input Network

### Description

This signaling network is the reduced COSMOS network solution obtained in the case study of the COSMOS paper. Here, this network solution is reused as an exemplary input prior knowledge network (PKN).

### Usage

    data(toy_network)

### Format

An object of class “`data.frame`” with 19 rows (interactions) and three variables:

`source`

  Source node, either metabolite or protein

`interaction`

  Type of interaction, 1 = Activation, -1 = Inhibition

`target`

  Target node, either metabolite or protein

A detailed description of the identifier formatting can be found under https://metapkn.omnipathdb.org/00__README.txt.

### Source

The network data are available on github: https://github.com/saezlab/COSMOS_MSB/tree/main/results/COSMOS_result/COSMOS_res_session.RData. The toy_network is the combined network of the COSMOS network solutions CARNIVAL_Result2 and CARNIVAL_Result_rerun subsequently reduced to 19 exemplary nodes.

### References

Dugourd, A., Kuppe, C. and Sciacovelli, M. et. al. (2021) Molecular Systems Biology. 17, e9730.

### Examples

    data(toy_network)

[Package cosmosR version 1.2.0 Index]