R: Calcualte The Gene Drug Sensitivity

geneDrugSensitivity {PharmacoGx}

R Documentation

Calcualte The Gene Drug Sensitivity

Description

TODO:: Write a description!

Usage

geneDrugSensitivity(
  x,
  type,
  batch,
  drugpheno,
  interaction.typexgene = FALSE,
  model = FALSE,
  standardize = c("SD", "rescale", "none"),
  verbose = FALSE
)

Arguments

`x`	A `numeric` vector of gene expression values
`type`	A `vector` of factors specifying the cell lines or type types
`batch`	A `vector` of factors specifying the batch
`drugpheno`	A `numeric` vector of drug sensitivity values (e.g., IC50 or AUC)
`interaction.typexgene`	`boolean` Should interaction between gene expression and cell/type type be computed? Default set to FALSE
`model`	`boolean` Should the full linear model be returned? Default set to FALSE
`standardize`	`character` One of 'SD', 'rescale' or 'none'
`verbose`	`boolean` Should the function display messages?

Value

A vector reporting the effect size (estimateof the coefficient of drug concentration), standard error (se), sample size (n), t statistic, and F statistics and its corresponding p-value.

[Package PharmacoGx version 2.6.0 Index]