| drugTargetInteractions-package {drugTargetInteractions} | R Documentation |
The drugTargetInteractions package provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database.
The DESCRIPTION file:
| Package: | drugTargetInteractions |
| Type: | Package |
| Title: | Drug-Target Interactions |
| Version: | 1.0.0 |
| Date: | 2021-03-22 |
| Authors@R: | person("Thomas", "Girke", email="thomas.girke@ucr.edu", role=c("cre", "aut")) |
| Description: | Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database. ChEMBL has been chosen for this purpose, because it provides one of the most comprehensive and best annotatated knowledge resources for drug-target information available in the public domain. |
| Depends: | methods, R (>= 4.1) |
| Imports: | utils, RSQLite, UniProt.ws, biomaRt,ensembldb, BiocFileCache,dplyr,rappdirs, AnnotationFilter, S4Vectors |
| Suggests: | RUnit, BiocStyle, knitr, rmarkdown, ggplot2, reshape2, DT, EnsDb.Hsapiens.v86 |
| VignetteBuilder: | knitr |
| License: | Artistic-2.0 |
| NeedsCompilation: | no |
| URL: | https://github.com/longevity-consortium/LC_Chemoinformatics |
| biocViews: | Cheminformatics, BiomedicalInformatics, Pharmacogenetics, Pharmacogenomics, Proteomics, Metabolomics |
| RoxygenNote: | 7.1.1 |
| BugReports: | https://github.com/girke-lab/drugTargetInteractions |
| git_url: | https://git.bioconductor.org/packages/drugTargetInteractions |
| git_branch: | RELEASE_3_13 |
| git_last_commit: | be807a4 |
| git_last_commit_date: | 2021-05-19 |
| Date/Publication: | 2021-05-19 |
| Author: | Thomas Girke [cre, aut] |
| Maintainer: | Thomas Girke <thomas.girke@ucr.edu> |
Index of help topics:
cmpIdMapping cmpIdMapping
downloadChemblDb downloadChemblDb
downloadUniChem downloadUniChem
drugTargetAnnot drugTargetAnnot
drugTargetAnnotTable drugTargetAnnotTable
drugTargetBioactivity drugTargetBioactivity
drugTargetInteractions-package
Drug-Target Interactions
genConfig genConfig
getDrugTarget getDrugTarget
getParalogs getParalogs
getSymEnsUp Gene to Protein ID Mappings
getUniprotIDs Retrieve UniProt IDs via ID and Cluster
Mappings
processDrugage processDrugage
runDrugTarget_Annot_Bioassay
runDrugTarget_Annot_Bioassay
transformTTD transformTTD
NA
Maintainer: NA