R: Simple simulation

simpleSimulate {splatter}

R Documentation

Simple simulation

Description

Simulate counts from a simple negative binomial distribution without simulated library sizes, differential expression etc.

Usage

simpleSimulate(params = newSimpleParams(), verbose = TRUE, ...)

Arguments

`params`	SimpleParams object containing simulation parameters.
`verbose`	logical. Whether to print progress messages
`...`	any additional parameter settings to override what is provided in `params`.

Details

Gene means are simulated from a gamma distribution with shape = mean.shape and rate = mean.rate. Counts are then simulated from a negative binomial distribution with mu = means and size = 1 / counts.disp. See SimpleParams for more details of the parameters.

Value

SingleCellExperiment containing simulated counts

Examples

sim <- simpleSimulate()
# Override default parameters
sim <- simpleSimulate(nGenes = 1000, nCells = 50)

[Package splatter version 1.11.4 Index]