cxds_bcds_hybrid {scds} | R Documentation

## Find doublets/multiples in UMI scRNA-seq data;

### Description

Annotates doublets/multiplets using the hybrid approach

### Usage

    cxds_bcds_hybrid(sce, cxdsArgs = NULL, bcdsArgs = NULL, verb = FALSE,
      estNdbl = FALSE, force = FALSE)

### Arguments

`sce` | single cell experiment (`SingleCellExperiment`) object to analyze; needs `counts` in assays slot.
`cxdsArgs` | list, arguments for cxds function in list form. Default: NULL
`bcdsArgs` | list, arguments for bcds function in list form. Default: NULL
`verb` | logical, switch on/off progress messages
`estNdbl` | logical, should the numer of doublets be estimated from the data. Enables doublet calls. Default:FALSE. Use with caution.
`force` | logical, force a (re)run of `cxds` and `bcds`. Default: FALSE

### Value

sce input sce object `SingleCellExperiment` with doublet scores added to colData as "hybrid_score" column.

### Examples

    data("sce_chcl")
    ## create small data set using only 100 cells
    sce_chcl_small = sce_chcl[, 1:100]
    sce_chcl_small = cxds_bcds_hybrid(sce_chcl_small)

[Package scds version 1.3.0 Index]