R: Compare genes to known TCGA drivers and their biological...

tcgaDriverBP {maftools}

R Documentation

Compare genes to known TCGA drivers and their biological pathways

Description

A small function which uses known cancer driver genes and their associatd pathways from TCGA cohorts. See reference for details

Usage

tcgaDriverBP(m, top = 50)

Arguments

`m`	an `MAF` object
`top`	Top number of genes to use. Default 50

References

Bailey MH, Tokheim C, Porta-Pardo E, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations . Cell. 2018;173(2):371–385.e18. doi:10.1016/j.cell.2018.02.060

Examples

laml.maf <- system.file("extdata", "tcga_laml.maf.gz", package = "maftools")
laml <- read.maf(maf = laml.maf)
tcgaDriverBP(m = laml)

[Package maftools version 2.3.30 Index]