picsFDR {PICS}R Documentation

Estimate the FDR

Description

Estimate the false detection rate for an object of class pics or picsList.

Usage

picsFDR(
  picsIP,
  picsCont,
  filter = list(delta = c(0, Inf), se = c(0, Inf), sigmaSqF = c(0, Inf), sigmaSqR = c(0,
    Inf))
)

Arguments

picsIP

An object of class pics or picsList containing the informations for the IP reads.

picsCont

An object of class pics or picsList containing the informations for the control reads

filter

A list of ranges for filtering regions based on PICS parameters. By default filter is set to NULL and all regions are used.

  • delta: Length of the binding sites

  • se: Standard error

  • sigmaSqF: Forward peak variance

  • sigmaSqR: Reverse peak variance

Value

A data.frame with the following columns: FDR, score, N

See Also

picsList pics

[Package PICS version 2.31.5 Index]