ct.GREATdb {gCrisprTools}R Documentation

Update a gene-centric msdb object for GREAT-style enrichment analysis using a specified CRISPR annotation.

Description

Update a gene-centric msdb object for GREAT-style enrichment analysis using a specified CRISPR annotation.

Usage

ct.GREATdb(
  annotation,
  gsdb = getMSigGeneSetDb(c("h", "c2"), "human"),
  minsize = 10
)

Arguments

annotation

an annotation object returned by ct.prepareAnnotation().

gsdb

A gene-centric GeneSetDb object to conform to the relevant peakwise dataset.

minsize

Minimum number of targets required to consider a geneset valid for analysis.

Value

A new GeneSetDb object with the features annotated genewise to pathways.

[Package gCrisprTools version 1.16.0 Index]