# Tools for curating, analyzing, and manipulating biological sequences

## Documentation for package ‘DECIPHER’ version 2.16.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

DECIPHER-package | Tools for curating, analyzing, and manipulating biological sequences
AA_REDUCED | Reduced amino acid alphabets
Add2DB | Add Data to a Database
AdjustAlignment | Improve An Existing Alignment By Adjusting Gap Placements
AlignDB | Align Two Sets of Aligned Sequences in a Sequence Database
AlignProfiles | Align Two Sets of Aligned Sequences
AlignSeqs | Align a Set of Unaligned Sequences
AlignSynteny | Pairwise Aligns Syntenic Blocks
AlignTranslation | Align Sequences By Their Amino Acid Translation
AmplifyDNA | Simulate Amplification of DNA by PCR
Array2Matrix | Create a Matrix Representation of a Microarray
BrowseDB | View a Database Table in a Web Browser
BrowseSeqs | View Sequences in a Web Browser
c.Taxa | Taxa training and testing objects
CalculateEfficiencyArray | Predict the Hybridization Efficiency of Probe/Target Sequence Pairs
CalculateEfficiencyFISH | Predict Thermodynamic Parameters of Probe/Target Sequence Pairs
CalculateEfficiencyPCR | Predict Amplification Efficiency of Primer Sequences
Codec | Compression/Decompression of Character Vectors
ConsensusSequence | Create a Consensus Sequence
Cophenetic | Compute cophenetic distances on dendrogram objects
CorrectFrameshifts | Corrects Frameshift Errors In Protein Coding Sequences
CreateChimeras | Create Artificial Chimeras
DB2Seqs | Export Database Sequences to a FASTA or FASTQ File
DECIPHER | Tools for curating, analyzing, and manipulating biological sequences
deltaGrules | Free Energy of Hybridization of Probe/Target Quadruplets on Microarrays
deltaHrules | Change in Enthalpy of Hybridization of Primer/Target Quadruplets in Solution
deltaSrules | Change in Entropy of Hybridization of Primer/Target Quadruplets in Solution
DesignArray | Design a Set of DNA Microarray Probes for Detecting Sequences
DesignPrimers | Design PCR Primers Targeting a Specific Group of Sequences
DesignProbes | Design FISH Probes Targeting a Specific Group of Sequences
DesignSignatures | Design PCR Primers for Amplifying Group-Specific Signatures
DigestDNA | Simulate Restriction Digestion of DNA
Disambiguate | Expand Ambiguities into All Permutations of a DNAStringSet
DistanceMatrix | Calculate the Distances Between Sequences
FindChimeras | Find Chimeras in a Sequence Database
FindSynteny | Finds Synteny in a Sequence Database
FormGroups | Forms Groups By Rank
HEC_MI1 | Mutual Information for Protein Secondary Structure Prediction
HEC_MI2 | Mutual Information for Protein Secondary Structure Prediction
IdClusters | Cluster Sequences By Distance or Sequence
IdConsensus | Create Consensus Sequences by Groups
IdentifyByRank | Identify By Taxonomic Rank
IdLengths | Determine the Number of Bases, Nonbases, and Width of Each Sequence
IdTaxa | Assign Sequences a Taxonomic Classification
LearnTaxa | Train a Classifier for Assigning Taxonomy
MapCharacters | Map Changes in Ancestral Character States
MaskAlignment | Mask Highly Variable Regions of An Alignment
MeltDNA | Simulate Melting of DNA
MIQS | MIQS Amino Acid Substitution Matrix
MODELS | Available Models of DNA Evolution
NNLS | Sequential Coordinate-wise Algorithm for the Non-negative Least Squares Problem
OrientNucleotides | Orient Nucleotide Sequences
pairs.Synteny | Synteny blocks and hits
PFASUM | PFASUM Amino Acid Substitution Matrices
plot.Synteny | Synteny blocks and hits
plot.Taxa | Taxa training and testing objects
PredictDBN | Predict RNA Secondary Structure in Dot-Bracket Notation
PredictHEC | Predict Protein Secondary Structure as Helix, Beta-Sheet, or Coil
print.Synteny | Synteny blocks and hits
print.Taxa | Taxa training and testing objects
ReadDendrogram | Read a Dendrogram from a Newick Formatted File
RemoveGaps | Remove Gap Characters in Sequences
RESTRICTION_ENZYMES | Common Restriction Enzyme's Cut Sites
SearchDB | Obtain Specific Sequences from a Database
Seqs2DB | Add Sequences from Text File to Database
StaggerAlignment | Produce a Staggered Alignment
Synteny-class | Synteny blocks and hits
Taxa-class | Taxa training and testing objects
TerminalChar | Determine the Number of Terminal Characters
TileSeqs | Form a Set of Tiles for Each Group of Sequences.
TrainingSet_16S | Training Set for Classification of 16S rRNA Gene Sequences
TrimDNA | Trims DNA Sequences to the High Quality Region Between Patterns
WriteDendrogram | Write a Dendrogram to Newick Format
[.Synteny | Synteny blocks and hits
[.Taxa | Taxa training and testing objects