ResembleDepmap {MAGeCKFlute} | R Documentation

## Compute the similarity between customized CRISPR screen with Depmap screens

### Description

Compute the similarity between customized CRISPR screen with Depmap screens

### Usage

    ResembleDepmap(dd, symbol = "id", score = "Score", lineages = "All",
      method = c("pearson", "spearman", "kendall")[1])

### Arguments

`dd` | A data frame.
`symbol` | A character, specifying the column name of gene symbols in the data frame.
`score` | A character, specifying the column name of gene essentiality score in the data frame.
`lineages` | A character vector, specifying the lineages used for common essential gene selection.
`method` | A character, indicating which correlation coefficient is to be used for the test. One of "pearson", "kendall", or "spearman".

### Value

A data frame with correlation and test p.value.

### Author(s)

Wubing Zhang

### Examples

    dd.rra = ReadRRA(rra.gene_summary)
    ## Not run:
      rra.omit = OmitCommonEssential(dd.rra)
      depmap_similarity = ResembleDepmap(rra.omit)
      head(depmap_similarity)

    ## End(Not run)

[Package MAGeCKFlute version 1.6.5 Index]