MIPS Gold Standard Protein Interactions

Description

The MIPS gold standard protein complex data set downloaded from the Gerstein Lab web site.

Usage

data(MIPSGS)

Format

A data frame with 8617 observations on the following 5 variables.

ORF1

The ORF for one gene

ORF2

The ORF for the second gene

CID

The MIPS protein complex ID

NAME

The name of the complex.

NUMBER

The number of proteins in the complex.

Details

The data are essentially multiprotein complexes, curated from MIPS data, see also the data set in Mpact, which is related.

The data are all pairwise members of each complex.

Yu et al. state “ To compile a reference data set with the lowest false-positive rate, we consider two proteins as interaction part- ners if and only if they are in the same complex of the highest level in the catalog. ”

Source

http://interolog.gersteinlab.org

References

Annotation Transfer Between Genomes: Protein-Protein Interologs and Protein-DNA Regulogs, H. Yu et al, Genome Research, 1107-1118, 2004.

Examples

data(MIPSGS)