drosophila2ENZYME {drosophila2.db} | R Documentation

## Map between Manufacturer IDs and Enzyme Commission (EC) Numbers

### Description

drosophila2ENZYME is an R object that provides mappings between manufacturer identifiers and EC numbers.

### Details

Each manufacturer identifier maps to a named vector containing the EC number that corresponds to the enzyme produced by that gene. The name corresponds to the manufacturer identifier. If this information is unknown, the vector will contain an `NA`.

Enzyme Commission numbers are assigned by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology http://www.chem.qmw.ac.uk/iubmb/enzyme/ to allow enzymes to be identified.

An Enzyme Commission number is of the format EC x.y.z.w, where x, y, z, and w are numeric numbers. In drosophila2ENZYME2PROBE, EC is dropped from the Enzyme Commission numbers.

Enzyme Commission numbers have corresponding names that describe the functions of enzymes in such a way that EC x is a more general description than EC x.y that in turn is a more general description than EC x.y.z. The top level EC numbers and names are listed below:

EC 1 oxidoreductases

EC 2 transferases

EC 3 hydrolases

EC 4 lyases

EC 5 isomerases

EC 6 ligases

The EC name for a given EC number can be viewed at http://www.chem.qmul.ac.uk/iupac/jcbn/index.html#6

Mappings between probe identifiers and enzyme identifiers were obtained using files provided by: KEGG GENOME ( ftp://ftp.genome.jp/pub/kegg/genomes ) on 2009-Mar10 For fly, this required mapping these ids THROUGH the flybase IDs provided by NCBI.

### References

ftp://ftp.genome.ad.jp/pub/kegg/pathways

### Examples

            x <- drosophila2ENZYME
            # Get the probe identifiers that are mapped to an EC number
            mapped_probes <- mappedkeys(x)
            # Convert to a list
            xx <- as.list(x[mapped_probes])
            if(length(xx) > 0) {
              # Get the ENZYME for the first five probes
              xx[1:5]
              # Get the first one
              xx[[1]]
            }

[Package drosophila2.db version 2.2.11 Index]