RankingWelchT {GeneSelector} | R Documentation

## Ranking based on the Welch t statistic.

### Description

Performs univariate (rowwise) Welch tests on a gene expression matrix. The Welch t statistic is a better alternative to the 'ordinary' t statistic in the two sample, unequal variances setting.
For `S4` method information, see RankingWelchT-methods.

### Usage

    RankingWelchT(x, y, type = "unpaired", pvalues = TRUE, gene.names = NULL, ...)

### Arguments

`x` | A `matrix` of gene expression values with rows corresponding to genes and columns corresponding to observations or alternatively an object of class `ExpressionSet`.
`y` | If `x` is a matrix, then `y` may be a `numeric` vector or a factor with at most two levels. If `x` is an `ExpressionSet`, then `y` is a character specifying the phenotype variable in the output from `pData`.
`type` | Only the two sample case, `type="unpaired"` is possible. Otherwise, use RankingTstat. Variances are assumed to be unequal.
`pvalues` | Should p-values be computed ? Default is `TRUE`.
`gene.names` | An optional vector of gene names.
`...` | Currenly unused argument.

### Value

An object of class GeneRanking.

### Author(s)

Martin Slawski martin.slawski@campus.lmu.de
Anne-Laure Boulesteix http://www.slcmsr.net/boulesteix

### See Also

GetRepeatRanking, RankingTstat, RankingFC, RankingWilcoxon, RankingBaldiLong, RankingFoxDimmic, RankingLimma, RankingEbam, RankingWilcEbam, RankingSam, RankingBstat, RankingShrinkageT, RankingSoftthresholdT, RankingPermutation, RankingGap

### Examples

    ## Load toy gene expression data
    data(toydata)
    ### class labels
    yy <- toydata[1,]
    ### gene expression
    xx <- toydata[-1,]
    ### run RankingWelch
    welchT <- RankingWelchT(xx, yy, type="unpaired")

[Package GeneSelector version 1.2.0 Index]