Package: birta
Version: 1.8.0
Date: 2013-03-07
Title: Bayesian Inference of Regulation of Transcriptional Activity
Author: Benedikt Zacher, Khalid Abnaof, Stephan Gade, Erfan Younesi,
        Achim Tresch, Holger Froehlich
Maintainer: Benedikt Zacher <zacher@lmb.uni-muenchen.de>, Holger
 Froehlich <frohlich@bit.uni-bonn.de>
Depends: limma, MASS, R(>= 2.10), Biobase, methods
Description: Expression levels of mRNA molecules are regulated by
        different processes, comprising inhibition or activation by
        transcription factors and post-transcriptional degradation by
        microRNAs. birta (Bayesian Inference of Regulation of
        Transcriptional Activity) uses the regulatory networks of TFs
        and miRNAs together with mRNA and miRNA expression data to
        predict switches in regulatory activity between two conditions.
        A Bayesian network is used to model the regulatory structure
        and Markov-Chain-Monte-Carlo is applied to sample the activity
        states.
License: GPL (>= 2)
LazyLoad: yes
Packaged: 2014-04-12 09:54:26 UTC; biocbuild
biocViews: Microarray, Sequencing, GeneExpression, Transcription,
        GraphAndNetwork
Built: R 3.1.0; i386-w64-mingw32; 2014-04-12 11:48:43 UTC; windows
Archs: i386, x64
