Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

Documentation for package ‘HD2013SGI’ version 1.00.1

HD2013SGI-package	Experimental Data and Analysis of the HCT116 Genetic Interaction Matrix
datamatrix	Phenotypic data after quality control and feature selection
datamatrixfull	Phenotypic data before quality control and feature selection
featuresPerWell	Original phenotypic measurements in screen order
HD2013SGI	Experimental Data and Analysis of the HCT116 Genetic Interaction Matrix
HD2013SGIHeatmapHuman	Plotting heatmaps of genetic interaction scores
HD2013SGImaineffects	Estimation of main effects
HD2013SGIorderDim	hclust on one out of three dimensions of an interaction matrix
HD2013SGIselectByStability	Feature selection method
Interactions	The genetic interaction data.
mainEffects	Estimated main effects
nrOfInteractionsPerTarget	Number of interactions per target gene
QueryAnnotation	Annotation of all query genes in the screen
stabilitySelection	Results from the feature selection method
TargetAnnotation	Annotation of all target genes in the screen