LunParams {splatter} | R Documentation

## The LunParams class

### Description

S4 class that holds parameters for the Lun simulation.

### Parameters

The Lun simulation uses the following parameters:

`nGenes`

  The number of genes to simulate.

`nCells`

  The number of cells to simulate.

`[nGroups]`

  The number of groups to simulate.

`[groupCells]`

  Vector giving the number of cells in each simulation group/path.

`[seed]`

  Seed to use for generating random numbers.

Mean parameters
  `[mean.shape]`

    Shape parameter for the mean gamma distribution.

  `[mean.rate]`

    Rate parameter for the mean gamma distribution.

Counts parameters
  `[count.disp]`

    The dispersion parameter for the counts negative binomial distribution.

Differential expression parameters
  `[de.nGenes]`

    The number of genes that are differentially expressed in each group

  `[de.upProp]`

    The proportion of differentially expressed genes that are up-regulated in each group

  `[de.upFC]`

    The fold change for up-regulated genes

  `[de.downFC]`

    The fold change for down-regulated genes

The parameters not shown in brackets can be estimated from real data using `lunEstimate`. For details of the Lun simulation see `lunSimulate`.

[Package splatter version 1.4.3 Index]