st.gallen {genefu} | R Documentation

## Function to compute the St Gallen consensus criterion for prognostication

### Description

This function computes the updated St Gallen consensus criterions as published by Goldhirsh et al 2003.

### Usage

    st.gallen(size, grade, node, her2.neu, age, vascular.inv, na.rm = FALSE)

### Arguments

`size` | tumor size in cm.
`grade` | Histological grade, i.e. low (1), intermediate (2) and high (3) grade.
`node` | Nodal status (0 or 1 for no lymph node invasion a,d at least 1 invaded lymph ode respectively).
`her2.neu` | Her2/neu status (0 or 1).
`age` | Age at diagnosis (in years).
`vascular.inv` | Peritumoral vascular invasion (0 or 1).
`na.rm` | `TRUE` if missing values should be removed, `FALSE` otherwise.

### Value

Vector of risk predictions: "Good", "Intermediate", and "Poor".

### Author(s)

Benjamin Haibe-Kains

### References

Goldhirsh A, Wood WC, Gelber RD, Coates AS, Thurlimann B, and Senn HJ (2003) "Meeting highlights: Updated international expert consensus on the primary therapy of early breast cancer", Journal of Clinical Oncology, 21(17):3357–3365.

### See Also

`npi`

### Examples

    ## load NKI dataset
    data(NKI)
    ## compute St Gallen predictions
    st.gallen(size=demo.nkis[ ,"size"], grade=demo.nkis[ ,"grade"],
      node=demo.nkis[ ,"node"], her2.neu=sample(x=0:1, size=nrow(demo.nkis),
      replace=TRUE), age=demo.nkis[ ,"age"], vascular.inv=sample(x=0:1,
      size=nrow(demo.nkis), replace=TRUE), na.rm=TRUE)

[Package genefu version 2.12.0 Index]