rnb.execute.lump {RnBeads} | R Documentation

## Leukocytes unmethylation for purity

### Description

Implementation of the LUMP (Leukocytes UnMethylation for Purity) algorithm for purity estimation on methylation datasets.

### Usage

    rnb.execute.lump(dataset)

### Arguments

`dataset` | Methylation dataset to study, provided as an object of type inheriting `RnBSet`.

### Details

The LUMP algorithm is developed by Dvir Aran, Marina Sirota and Atul J. Buttea.

### Value

Purity esimates provided as a `vector` of values in the range `[0, 1]`. The attribute `"sites"` contains the number of sites used in estimating the immune cell proportions. In case the dataset does not contain measurements for any of the sites on which LUMP focuses, the return values is `NULL`.

### Author(s)

Yassen Assenov

[Package RnBeads version 1.12.1 Index]