directionalityIndex {HiTC} | R Documentation

## Directionality index calculation

### Description

Calculate the directionality index as proposed by Dixon et al. 2012

### Usage

    directionalityIndex(x, winup = 2e+06, windown = 2e+06)

### Arguments

`x` | `HTClist` object
`winup` | size of upstream window
`windown` | size of downstrean window

### Details

Calculate the directionality index as proposed by Dixon et al. This index is then used to call topological domains in Hi-C/5C data.

### Value

A `numeric` vector

### Author(s)

N. Servant

### See Also

`HTClist-class`

### Examples

    require(HiCDataHumanIMR90)
    data(Dixon2012_IMR90)
    hox <- extractRegion(hic_imr90_40$chr6chr6, chr="chr6", from=50e6, to=58e6)
    di<-directionalityIndex(hox)

[Package HiTC version 1.24.0 Index]