## KEGG Orthology (KO)

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     01100 Metabolism
       01101 Carbohydrate Metabolism
         00010 Glycolysis / Gluconeogenesis [PATH:ko00010]
         00020 Citrate cycle (TCA cycle) [PATH:ko00020]
         00030 Pentose phosphate pathway [PATH:ko00030]
         00040 Pentose and glucuronate interconversions [PATH:ko00040]
         00051 Fructose and mannose metabolism [PATH:ko00051]
         00052 Galactose metabolism [PATH:ko00052]
         00053 Ascorbate and aldarate metabolism [PATH:ko00053]
         00500 Starch and sucrose metabolism [PATH:ko00500]
         00520 Amino sugar and nucleotide sugar metabolism [PATH:ko00520]
         00620 Pyruvate metabolism [PATH:ko00620]
         00630 Glyoxylate and dicarboxylate metabolism [PATH:ko00630]
         00640 Propanoate metabolism [PATH:ko00640]
         00650 Butanoate metabolism [PATH:ko00650]
         00660 C5-Branched dibasic acid metabolism [PATH:ko00660]
         00562 Inositol phosphate metabolism [PATH:ko00562]
       01102 Energy Metabolism
         00190 Oxidative phosphorylation [PATH:ko00190]
         00195 Photosynthesis [PATH:ko00195]
         00196 Photosynthesis - antenna proteins [PATH:ko00196]
         00194 Photosynthesis proteins [BR:ko00194]
         00710 Carbon fixation in photosynthetic organisms [PATH:ko00710]
         00720 Reductive carboxylate cycle (CO2 fixation) [PATH:ko00720]
         00680 Methane metabolism [PATH:ko00680]
         00910 Nitrogen metabolism [PATH:ko00910]
         00920 Sulfur metabolism [PATH:ko00920]
       01103 Lipid Metabolism
         00061 Fatty acid biosynthesis [PATH:ko00061]
         00062 Fatty acid elongation in mitochondria [PATH:ko00062]
         00071 Fatty acid metabolism [PATH:ko00071]
         00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
         00100 Steroid biosynthesis [PATH:ko00100]
         00120 Primary bile acid biosynthesis [PATH:ko00120]
         00121 Secondary bile acid biosynthesis [PATH:ko00121]
         00140 Steroid hormone biosynthesis [PATH:ko00140]
         00561 Glycerolipid metabolism [PATH:ko00561]
         00564 Glycerophospholipid metabolism [PATH:ko00564]
         00565 Ether lipid metabolism [PATH:ko00565]
         00600 Sphingolipid metabolism [PATH:ko00600]
         00590 Arachidonic acid metabolism [PATH:ko00590]
         00591 Linoleic acid metabolism [PATH:ko00591]
         00592 alpha-Linolenic acid metabolism [PATH:ko00592]
         01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
         01004 Lipid biosynthesis proteins [BR:ko01004]
       01104 Nucleotide Metabolism
         00230 Purine metabolism [PATH:ko00230]
         00240 Pyrimidine metabolism [PATH:ko00240]
       01105 Amino Acid Metabolism
         00250 Alanine, aspartate and glutamate metabolism [PATH:ko00250]
         00260 Glycine, serine and threonine metabolism [PATH:ko00260]
         00270 Cysteine and methionine metabolism [PATH:ko00270]
         00280 Valine, leucine and isoleucine degradation [PATH:ko00280]
         00290 Valine, leucine and isoleucine biosynthesis [PATH:ko00290]
         00300 Lysine biosynthesis [PATH:ko00300]
         00310 Lysine degradation [PATH:ko00310]
         00330 Arginine and proline metabolism [PATH:ko00330]
         00340 Histidine metabolism [PATH:ko00340]
         00350 Tyrosine metabolism [PATH:ko00350]
         00360 Phenylalanine metabolism [PATH:ko00360]
         00380 Tryptophan metabolism [PATH:ko00380]
         00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:ko00400]
       01106 Metabolism of Other Amino Acids
         00410 beta-Alanine metabolism [PATH:ko00410]
         00430 Taurine and hypotaurine metabolism [PATH:ko00430]
         00440 Phosphonate and phosphinate metabolism [PATH:ko00440]
         00450 Selenoamino acid metabolism [PATH:ko00450]
         00460 Cyanoamino acid metabolism [PATH:ko00460]
         00471 D-Glutamine and D-glutamate metabolism [PATH:ko00471]
         00472 D-Arginine and D-ornithine metabolism [PATH:ko00472]
         00473 D-Alanine metabolism [PATH:ko00473]
         00480 Glutathione metabolism [PATH:ko00480]
       01107 Glycan Biosynthesis and Metabolism
         00510 N-Glycan biosynthesis [PATH:ko00510]
         00513 High-mannose type N-glycan biosynthesis [PATH:ko00513]
         00512 O-Glycan biosynthesis [PATH:ko00512]
         00514 O-Mannosyl glycan biosynthesis [PATH:ko00514]
         00532 Chondroitin sulfate biosynthesis [PATH:ko00532]
         00534 Heparan sulfate biosynthesis [PATH:ko00534]
         00533 Keratan sulfate biosynthesis [PATH:ko00533]
         00540 Lipopolysaccharide biosynthesis [PATH:ko00540]
         01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
         00550 Peptidoglycan biosynthesis [PATH:ko00550]
         00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH:ko00563]
         00601 Glycosphingolipid biosynthesis - lacto and neolacto series [PATH:ko00601]
         00603 Glycosphingolipid biosynthesis - globo series [PATH:ko00603]
         00604 Glycosphingolipid biosynthesis - ganglio series [PATH:ko00604]
         00531 Glycosaminoglycan degradation [PATH:ko00531]
         00511 Other glycan degradation [PATH:ko00511]
         01003 Glycosyltransferases [BR:ko01003]
         00535 Proteoglycans [BR:ko00535]
       01108 Biosynthesis of Polyketides and Nonribosomal Peptides
         01052 Type I polyketide structures [PATH:sma01052]
         00522 Biosynthesis of 12-, 14- and 16-membered macrolides [PATH:ko00522]
         01051 Biosynthesis of ansamycins [PATH:ko01051]
         01056 Biosynthesis of type II polyketide backbone [PATH:ko01056]
         01057 Biosynthesis of type II polyketide products [PATH:ko01057]
         00523 Polyketide sugar unit biosynthesis [PATH:ko00523]
         01054 Nonribosomal peptide structures [PATH:bsu01054]
         01053 Biosynthesis of siderophore group nonribosomal peptides [PATH:ko01053]
         01055 Biosynthesis of vancomycin group antibiotics [PATH:ko01055]
       01109 Metabolism of Cofactors and Vitamins
         00730 Thiamine metabolism [PATH:ko00730]
         00740 Riboflavin metabolism [PATH:ko00740]
         00750 Vitamin B6 metabolism [PATH:ko00750]
         00760 Nicotinate and nicotinamide metabolism [PATH:ko00760]
         00770 Pantothenate and CoA biosynthesis [PATH:ko00770]
         00780 Biotin metabolism [PATH:ko00780]
         00785 Lipoic acid metabolism [PATH:ko00785]
         00790 Folate biosynthesis [PATH:ko00790]
         00670 One carbon pool by folate [PATH:ko00670]
         00830 Retinol metabolism [PATH:ko00830]
         00860 Porphyrin and chlorophyll metabolism [PATH:ko00860]
         00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:ko00130]
       01110 Biosynthesis of Secondary Metabolites
         00900 Terpenoid backbone biosynthesis [PATH:ko00900]
         00904 Diterpenoid biosynthesis [PATH:ko00904]
         00902 Monoterpenoid biosynthesis [PATH:ko00902]
         00903 Limonene and pinene degradation [PATH:ko00903]
         00908 Zeatin biosynthesis [PATH:ko00908]
         00909 Sesquiterpenoid biosynthesis [PATH:ko00909]
         00906 Carotenoid biosynthesis [PATH:ko00906]
         00905 Brassinosteroid biosynthesis [PATH:ko00905]
         00940 Phenylpropanoid biosynthesis [PATH:ko00940]
         00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis [PATH:ko00945]
         00941 Flavonoid biosynthesis [PATH:ko00941]
         00944 Flavone and flavonol biosynthesis [PATH:ko00944]
         00942 Anthocyanin biosynthesis [PATH:ko00942]
         00943 Isoflavonoid biosynthesis [PATH:ko00943]
         00901 Indole alkaloid biosynthesis [PATH:ko00901]
         00950 Isoquinoline alkaloid biosynthesis [PATH:ko00950]
         00960 Tropane, piperidine and pyridine alkaloid biosynthesis [PATH:ko00960]
         01058 Acridone alkaloid biosynthesis [PATH:ko01058]
         00232 Caffeine metabolism [PATH:ko00232]
         00965 Betalain biosynthesis [PATH:ko00965]
         00966 Glucosinolate biosynthesis [PATH:ko00966]
         00402 Benzoxazinoid biosynthesis [PATH:ko00402]
         00311 Penicillin and cephalosporin biosynthesis [PATH:ko00311]
         00312 beta-Lactam resistance [PATH:ko00312]
         00521 Streptomycin biosynthesis [PATH:ko00521]
         00253 Tetracycline biosynthesis [PATH:ko00253]
         00331 Clavulanic acid biosynthesis [PATH:ko00331]
         00231 Puromycin biosynthesis [PATH:ko00231]
         00401 Novobiocin biosynthesis [PATH:ko00401]
         00981 Insect hormone biosynthesis [PATH:ko00981]
       01111 Xenobiotics Biodegradation and Metabolism
         00930 Caprolactam degradation [PATH:ko00930]
         00621 Biphenyl degradation [PATH:ko00621]
         00622 Toluene and xylene degradation [PATH:ko00622]
         00361 gamma-Hexachlorocyclohexane degradation [PATH:ko00361]
         00641 3-Chloroacrylic acid degradation [PATH:ko00641]
         00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation [PATH:ko00351]
         00623 2,4-Dichlorobenzoate degradation [PATH:ko00623]
         00631 1,2-Dichloroethane degradation [PATH:ko00631]
         00625 Tetrachloroethene degradation [PATH:ko00625]
         00643 Styrene degradation [PATH:ko00643]
         00627 1,4-Dichlorobenzene degradation [PATH:ko00627]
         00626 Naphthalene and anthracene degradation [PATH:ko00626]
         00642 Ethylbenzene degradation [PATH:ko00642]
         00628 Fluorene degradation [PATH:ko00628]
         00629 Carbazole degradation [PATH:ko00629]
         00632 Benzoate degradation via CoA ligation [PATH:ko00632]
         00362 Benzoate degradation via hydroxylation [PATH:ko00362]
         00791 Atrazine degradation [PATH:ko00791]
         00363 Bisphenol A degradation [PATH:ko00363]
         00624 1- and 2-Methylnaphthalene degradation [PATH:ko00624]
         00633 Trinitrotoluene degradation [PATH:ko00633]
         00281 Geraniol degradation [PATH:ko00281]
         00364 Fluorobenzoate degradation [PATH:ko00364]
         00980 Metabolism of xenobiotics by cytochrome P450 [PATH:ko00980]
         00982 Drug metabolism - cytochrome P450 [PATH:ko00982]
         00983 Drug metabolism - other enzymes [PATH:ko00983]
       01112 Enzyme Families
         01000 Enzymes [BR:ko01000]
         01001 Protein kinases [BR:ko01001]
         01002 Peptidases [BR:ko01002]
         00199 Cytochrome P450 [BR:ko00199]
     01120 Genetic Information Processing
       01121 Transcription
         03020 RNA polymerase [PATH:ko03020]
         03022 Basal transcription factors [PATH:ko03022]
         03000 Transcription factors [BR:ko03000]
         03040 Spliceosome [PATH:ko03040]
         03041 Spliceosome [BR:ko03041]
       01122 Translation
         03010 Ribosome [PATH:ko03010]
         03011 Ribosome [BR:ko03011]
         03012 Translation factors [BR:ko03012]
         00970 Aminoacyl-tRNA biosynthesis [PATH:ko00970]
       01123 Folding, Sorting and Degradation
         03110 Chaperones and folding catalysts [BR:ko03110]
         04130 SNARE interactions in vesicular transport [PATH:ko04130]
         04131 SNAREs [BR:ko04131]
         04120 Ubiquitin mediated proteolysis [PATH:ko04120]
         04121 Ubiquitin system [BR:ko04121]
         03050 Proteasome [PATH:ko03050]
         03018 RNA degradation [PATH:ko03018]
       01124 Replication and Repair
         03030 DNA replication [PATH:ko03030]
         03032 DNA replication proteins [BR:ko03032]
         03036 Chromosome [BR:ko03036]
         03410 Base excision repair [PATH:ko03410]
         03420 Nucleotide excision repair [PATH:ko03420]
         03430 Mismatch repair [PATH:ko03430]
         03440 Homologous recombination [PATH:ko03440]
         03450 Non-homologous end-joining [PATH:ko03450]
         03400 DNA repair and recombination proteins [BR:ko03400]
     01130 Environmental Information Processing
       01131 Membrane Transport
         02000 Transporters [BR:ko02000]
         02010 ABC transporters [PATH:ko02010]
         02060 Phosphotransferase system (PTS) [PATH:ko02060]
         03070 Bacterial secretion system [PATH:ko03070]
         02044 Secretion system [BR:ko02044]
         03060 Protein export [PATH:ko03060]
       01132 Signal Transduction
         02020 Two-component system [PATH:ko02020]
         02022 Two-component system [BR:ko02022]
         04010 MAPK signaling pathway [PATH:ko04010]
         04013 MAPK signaling pathway - fly [PATH:ko04013]
         04011 MAPK signaling pathway - yeast [PATH:ko04011]
         04012 ErbB signaling pathway [PATH:ko04012]
         04310 Wnt signaling pathway [PATH:ko04310]
         04330 Notch signaling pathway [PATH:ko04330]
         04340 Hedgehog signaling pathway [PATH:ko04340]
         04350 TGF-beta signaling pathway [PATH:ko04350]
         04370 VEGF signaling pathway [PATH:ko04370]
         04630 Jak-STAT signaling pathway [PATH:ko04630]
         04020 Calcium signaling pathway [PATH:ko04020]
         04070 Phosphatidylinositol signaling system [PATH:ko04070]
         04150 mTOR signaling pathway [PATH:ko04150]
       01133 Signaling Molecules and Interaction
         04000 Receptors and channels [BR:ko04000]
         04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
         04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
         04052 Cytokines [BR:ko04052]
         04512 ECM-receptor interaction [PATH:ko04512]
         04514 Cell adhesion molecules (CAMs) [PATH:ko04514]
         04515 Cell adhesion molecules (CAMs) [BR:ko04515]
         04516 CAM ligands [BR:ko04516]
         04090 Cellular antigens [BR:ko04090]
         04031 GTP-binding proteins [BR:ko04031]
         04091 Glycan bindng proteins [BR:ko04091]
         02042 Bacterial toxins [BR:ko02042]
     01140 Cellular Processes
       01151 Transport and Catabolism
         04144 Endocytosis [PATH:ko04144]
         04142 Lysosome [PATH:ko04142]
         04146 Peroxisome [PATH:ko04146]
         04140 Regulation of autophagy [PATH:ko04140]
       01141 Cell Motility
         02030 Bacterial chemotaxis [PATH:ko02030]
         02035 Bacterial motility proteins [BR:ko02035]
         02040 Flagellar assembly [PATH:ko02040]
         04810 Regulation of actin cytoskeleton [PATH:ko04810]
         04812 Cytoskeleton proteins [BR:ko04812]
       01142 Cell Growth and Death
         04110 Cell cycle [PATH:ko04110]
         04111 Cell cycle - yeast [PATH:ko04111]
         04113 Meiosis - yeast [PATH:ko04113]
         04114 Oocyte meiosis [PATH:ko04114]
         04210 Apoptosis [PATH:ko04210]
         04115 p53 signaling pathway [PATH:ko04115]
       01143 Cell Communication
         04510 Focal adhesion [PATH:ko04510]
         04520 Adherens junction [PATH:ko04520]
         04530 Tight junction [PATH:ko04530]
         04540 Gap junction [PATH:ko04540]
     01150 Organismal Systems
       01145 Immune System
         04640 Hematopoietic cell lineage [PATH:ko04640]
         04610 Complement and coagulation cascades [PATH:ko04610]
         04620 Toll-like receptor signaling pathway [PATH:ko04620]
         04621 NOD-like receptor signaling pathway [PATH:ko04621]
         04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
         04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
         04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
         04612 Antigen processing and presentation [PATH:ko04612]
         04660 T cell receptor signaling pathway [PATH:ko04660]
         04662 B cell receptor signaling pathway [PATH:ko04662]
         04664 Fc epsilon RI signaling pathway [PATH:ko04664]
         04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
         04670 Leukocyte transendothelial migration [PATH:ko04670]
         04672 Intestinal immune network for IgA production [PATH:ko04672]
         04062 Chemokine signaling pathway [PATH:ko04062]
       01144 Endocrine System
         04910 Insulin signaling pathway [PATH:ko04910]
         04920 Adipocytokine signaling pathway [PATH:ko04920]
         03320 PPAR signaling pathway [PATH:ko03320]
         04912 GnRH signaling pathway [PATH:ko04912]
         04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
         04916 Melanogenesis [PATH:ko04916]
         04614 Renin-angiotensin system [PATH:ko04614]
       01152 Circulatory System
         04260 Cardiac muscle contraction [PATH:ko04260]
         04270 Vascular smooth muscle contraction [PATH:ko04270]
       01153 Excretory System
         04960 Aldosterone-regulated sodium reabsorption [PATH:ko04960]
       01146 Nervous System
         04720 Long-term potentiation [PATH:ko04720]
         04730 Long-term depression [PATH:ko04730]
         04722 Neurotrophin signaling pathway [PATH:ko04722]
       01147 Sensory System
         04740 Olfactory transduction [PATH:ko04740]
         04742 Taste transduction [PATH:ko04742]
       01148 Development
         04320 Dorso-ventral axis formation [PATH:ko04320]
         04360 Axon guidance [PATH:ko04360]
       01149 Environmental Adaptation
         04710 Circadian rhythm - mammal [PATH:ko04710]
         04711 Circadian rhythm - fly [PATH:ko04711]
         04712 Circadian rhythm - plant [PATH:ko04712]
         04626 Plant-pathogen interaction [PATH:ko04626]
     01160 Human Diseases
       01161 Cancers
         05200 Pathways in cancer [PATH:ko05200]
         05210 Colorectal cancer [PATH:ko05210]
         05212 Pancreatic cancer [PATH:ko05212]
         05214 Glioma [PATH:ko05214]
         05216 Thyroid cancer [PATH:ko05216]
         05221 Acute myeloid leukemia [PATH:ko05221]
         05220 Chronic myeloid leukemia [PATH:ko05220]
         05217 Basal cell carcinoma [PATH:ko05217]
         05218 Melanoma [PATH:ko05218]
         05211 Renal cell carcinoma [PATH:ko05211]
         05219 Bladder cancer [PATH:ko05219]
         05215 Prostate cancer [PATH:ko05215]
         05213 Endometrial cancer [PATH:ko05213]
         05222 Small cell lung cancer [PATH:ko05222]
         05223 Non-small cell lung cancer [PATH:ko05223]
       01162 Immune System Diseases
         05310 Asthma [PATH:ko05310]
         05322 Systemic lupus erythematosus [PATH:ko05322]
         05320 Autoimmune thyroid disease [PATH:ko05320]
         05330 Allograft rejection [PATH:ko05330]
         05332 Graft-versus-host disease [PATH:ko05332]
         05340 Primary immunodeficiency [PATH:ko05340]
       01163 Neurodegenerative Diseases
         05010 Alzheimer's disease [PATH:ko05010]
         05012 Parkinson's disease [PATH:ko05012]
         05014 Amyotrophic lateral sclerosis (ALS) [PATH:ko05014]
         05016 Huntington's disease [PATH:ko05016]
         05020 Prion diseases [PATH:ko05020]
       01166 Circulatory Diseases
         05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
         05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
         05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
         05416 Viral myocarditis [PATH:ko05416]
       01164 Metabolic Diseases
         04940 Type I diabetes mellitus [PATH:ko04940]
         04930 Type II diabetes mellitus [PATH:ko04930]
         04950 Maturity onset diabetes of the young [PATH:ko04950]
       01165 Infectious Diseases
         05110 Vibrio cholerae infection [PATH:ko05110]
         05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
         05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
         05130 Pathogenic Escherichia coli infection [PATH:ko05130]

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Last updated: March 1, 2010