## KEGG Orthology (KO)

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     01100 Metabolism

       01110 Carbohydrate Metabolism

         00010 Glycolysis / Gluconeogenesis [PATH:ko00010]
         00020 Citrate cycle (TCA cycle) [PATH:ko00020]
         00030 Pentose phosphate pathway [PATH:ko00030]
         00040 Pentose and glucuronate interconversions [PATH:ko00040]
         00051 Fructose and mannose metabolism [PATH:ko00051]
         00052 Galactose metabolism [PATH:ko00052]
         00053 Ascorbate and aldarate metabolism [PATH:ko00053]
         00500 Starch and sucrose metabolism [PATH:ko00500]
         00530 Aminosugars metabolism [PATH:ko00530]
         00520 Nucleotide sugars metabolism [PATH:ko00520]
         00620 Pyruvate metabolism [PATH:ko00620]
         00630 Glyoxylate and dicarboxylate metabolism [PATH:ko00630]
         00640 Propanoate metabolism [PATH:ko00640]
         00650 Butanoate metabolism [PATH:ko00650]
         00660 C5-Branched dibasic acid metabolism [PATH:ko00660]
         00031 Inositol metabolism [PATH:ko00031]
         00562 Inositol phosphate metabolism [PATH:ko00562]

       01120 Energy Metabolism

         00190 Oxidative phosphorylation [PATH:ko00190]
         00195 Photosynthesis [PATH:ko00195]
         00196 Photosynthesis - antenna proteins [PATH:ko00196]
         00710 Carbon fixation [PATH:ko00710]
         00720 Reductive carboxylate cycle (CO2 fixation) [PATH:ko00720]
         00680 Methane metabolism [PATH:ko00680]
         00910 Nitrogen metabolism [PATH:ko00910]
         00920 Sulfur metabolism [PATH:ko00920]
         00191 Pyruvate/Oxoglutarate oxidoreductases
         00192 ATPases

       01130 Lipid Metabolism

         00061 Fatty acid biosynthesis [PATH:ko00061]
         00062 Fatty acid elongation in mitochondria [PATH:ko00062]
         00071 Fatty acid metabolism [PATH:ko00071]
         00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
         00100 Biosynthesis of steroids [PATH:ko00100]
         00120 Bile acid biosynthesis [PATH:ko00120]
         00140 C21-Steroid hormone metabolism [PATH:ko00140]
         00150 Androgen and estrogen metabolism [PATH:ko00150]
         00561 Glycerolipid metabolism [PATH:ko00561]
         00564 Glycerophospholipid metabolism [PATH:ko00564]
         00565 Ether lipid metabolism [PATH:ko00565]
         00600 Sphingolipid metabolism [PATH:ko00600]
         00590 Arachidonic acid metabolism [PATH:ko00590]
         00591 Linoleic acid metabolism [PATH:ko00591]

       01140 Nucleotide Metabolism

         00230 Purine metabolism [PATH:ko00230]
         00240 Pyrimidine metabolism [PATH:ko00240]

       01150 Amino Acid Metabolism

         00251 Glutamate metabolism [PATH:ko00251]
         00252 Alanine and aspartate metabolism [PATH:ko00252]
         00260 Glycine, serine and threonine metabolism [PATH:ko00260]
         00271 Methionine metabolism [PATH:ko00271]
         00272 Cysteine metabolism [PATH:ko00272]
         00280 Valine, leucine and isoleucine degradation [PATH:ko00280]
         00290 Valine, leucine and isoleucine biosynthesis [PATH:ko00290]
         00300 Lysine biosynthesis [PATH:ko00300]
         00310 Lysine degradation [PATH:ko00310]
         00330 Arginine and proline metabolism [PATH:ko00330]
         00340 Histidine metabolism [PATH:ko00340]
         00350 Tyrosine metabolism [PATH:ko00350]
         00360 Phenylalanine metabolism [PATH:ko00360]
         00380 Tryptophan metabolism [PATH:ko00380]
         00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:ko00400]
         00220 Urea cycle and metabolism of amino groups [PATH:ko00220]

       01160 Metabolism of Other Amino Acids

         00410 beta-Alanine metabolism [PATH:ko00410]
         00430 Taurine and hypotaurine metabolism [PATH:ko00430]
         00440 Aminophosphonate metabolism [PATH:ko00440]
         00450 Selenoamino acid metabolism [PATH:ko00450]
         00460 Cyanoamino acid metabolism [PATH:ko00460]
         00471 D-Glutamine and D-glutamate metabolism [PATH:ko00471]
         00472 D-Arginine and D-ornithine metabolism [PATH:ko00472]
         00473 D-Alanine metabolism [PATH:ko00473]
         00480 Glutathione metabolism [PATH:ko00480]

       01170 Glycan Biosynthesis and Metabolism

         00510 N-Glycan biosynthesis [PATH:ko00510]
         00513 High-mannose type N-glycan biosynthesis [PATH:ko00513]
         00511 N-Glycan degradation [PATH:ko00511]
         00512 O-Glycan biosynthesis [PATH:ko00512]
         00532 Chondroitin sulfate biosynthesis [PATH:ko00532]
         00534 Heparan sulfate biosynthesis [PATH:ko00534]
         00533 Keratan sulfate biosynthesis [PATH:ko00533]
         00531 Glycosaminoglycan degradation [PATH:ko00531]
         00540 Lipopolysaccharide biosynthesis [PATH:ko00540]
         00550 Peptidoglycan biosynthesis [PATH:ko00550]
         00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH:ko00563]
         00601 Glycosphingolipid biosynthesis - lactoseries [PATH:ko00601]
         00602 Glycosphingolipid biosynthesis - neo-lactoseries [PATH:ko00602]
         00603 Glycosphingolipid biosynthesis - globoseries [PATH:ko00603]
         00604 Glycosphingolipid biosynthesis - ganglioseries [PATH:ko00604]

       01180 Biosynthesis of Polyketides and Nonribosomal Peptides

         01052 Type I polyketide structures [PATH:sma01052]
         00522 Biosynthesis of 12-, 14- and 16-membered macrolides [PATH:ko00522]
         01051 Biosynthesis of ansamycins [PATH:ko01051]
         01056 Biosynthesis of type II polyketide backbone [PATH:ko01056]
         01057 Biosynthesis of type II polyketide products [PATH:ko01057]
         00523 Polyketide sugar unit biosynthesis [PATH:ko00523]
         01054 Nonribosomal peptide structures [PATH:bsu01054]
         01053 Biosynthesis of siderophore group nonribosomal peptides [PATH:ko01053]
         01055 Biosynthesis of vancomycin group antibiotics [PATH:ko01055]

       01190 Metabolism of Cofactors and Vitamins

         00730 Thiamine metabolism [PATH:ko00730]
         00740 Riboflavin metabolism [PATH:ko00740]
         00750 Vitamin B6 metabolism [PATH:ko00750]
         00760 Nicotinate and nicotinamide metabolism [PATH:ko00760]
         00770 Pantothenate and CoA biosynthesis [PATH:ko00770]
         00780 Biotin metabolism [PATH:ko00780]
         00790 Folate biosynthesis [PATH:ko00790]
         00670 One carbon pool by folate [PATH:ko00670]
         00830 Retinol metabolism [PATH:ko00830]
         00860 Porphyrin and chlorophyll metabolism [PATH:ko00860]
         00130 Ubiquinone biosynthesis [PATH:ko00130]

       01195 Biosynthesis of Secondary Metabolites

         00900 Terpenoid biosynthesis [PATH:ko00900]
         00902 Monoterpenoid biosynthesis [PATH:ko00902]
         00903 Limonene and pinene degradation [PATH:ko00903]
         00904 Diterpenoid biosynthesis [PATH:ko00904]
         00906 Carotenoid biosynthesis [PATH:ko00906]
         00905 Brassinosteroid biosynthesis [PATH:ko00905]
         00901 Indole and ipecac alkaloid biosynthesis [PATH:ko00901]
         00940 Coumarine and phenylpropanoid biosynthesis [PATH:ko00940]
         00941 Flavonoid biosynthesis [PATH:ko00941]
         00950 Alkaloid biosynthesis I [PATH:ko00950]
         00960 Alkaloid biosynthesis II [PATH:ko00960]
         01058 Acridone alkaloid biosynthesis [PATH:ko01058]
         00311 Penicillin and cephalosporin biosynthesis [PATH:ko00311]
         00312 beta-Lactam resistance [PATH:ko00312]
         00521 Streptomycin biosynthesis [PATH:ko00521]
         00253 Tetracycline biosynthesis [PATH:ko00253]
         00331 Clavulanic acid biosynthesis [PATH:ko00331]
         00231 Puromycin biosynthesis [PATH:ko00231]
         00401 Novobiocin biosynthesis [PATH:ko00401]
         00402 Benzoxazinone biosynthesis [PATH:map00402]

       01196 Xenobiotics Biodegradation and Metabolism

         00930 Caprolactam degradation [PATH:ko00930]
         00621 Biphenyl degradation [PATH:ko00621]
         00622 Toluene and xylene degradation [PATH:ko00622]
         00361 gamma-Hexachlorocyclohexane degradation [PATH:ko00361]
         00641 3-Chloroacrylic acid degradation [PATH:ko00641]
         00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation [PATH:ko00351]
         00623 2,4-Dichlorobenzoate degradation [PATH:ko00623]
         00631 1,2-Dichloroethane degradation [PATH:ko00631]
         00625 Tetrachloroethene degradation [PATH:ko00625]
         00643 Styrene degradation [PATH:ko00643]
         00627 1,4-Dichlorobenzene degradation [PATH:ko00627]
         00626 Nitrobenzene degradation [PATH:ko00626]
         00642 Ethylbenzene degradation [PATH:ko00642]
         00628 Fluorene degradation [PATH:ko00628]
         00629 Carbazole degradation [PATH:ko00629]
         00632 Benzoate degradation via CoA ligation [PATH:ko00632]
         00362 Benzoate degradation via hydroxylation [PATH:ko00362]
         00791 Atrazine degradation [PATH:ko00791]
         00363 Bisphenol A degradation [PATH:ko00363]
         00624 1- and 2-Methylnaphthalene degradation [PATH:ko00624]
         00980 Metabolism of xenobiotics by cytochrome P450 [PATH:ko00980]

     01200 Genetic Information Processing

       01210 Transcription

         03020 RNA polymerase [PATH:ko03020]
         03022 Basal transcription factors [PATH:ko03022]
         03028 Other transcription related proteins
         03040 Spliceosome

       01220 Translation

         03010 Ribosome [PATH:ko03010]
         00970 Aminoacyl-tRNA biosynthesis [PATH:ko00970]
         03014 Other translation proteins

       01230 Folding, Sorting and Degradation

         03060 Protein export [PATH:ko03060]
         03090 Type II secretion system [PATH:ko03090]
         03070 Type III secretion system [PATH:ko03070]
         03080 Type IV secretion system [PATH:ko03080]
         03100 Protein folding and associated processing
         04130 SNARE interactions in vesicular transport [PATH:ko04130]
         04140 Regulation of autophagy [PATH:ko04140]
         04120 Ubiquitin mediated proteolysis [PATH:ko04120]
         03050 Proteasome [PATH:ko03050]
         03018 RNA degradosome

       01240 Replication and Repair

         03030 DNA polymerase [PATH:ko03030]
         03032 Replication complex
         03034 Other replication, recombination and repair proteins

     01300 Environmental Information Processing

       01310 Membrane Transport

         02010 ABC transporters [PATH:ko02010]
         02052 Other ion-coupled transporters
         02070 Pores ion channels
         02080 Electron transfer carriers
         02082 Other transporters
         02060 Phosphotransferase system (PTS) [PATH:ko02060]

       01320 Signal Transduction

         02020 Two-component system [PATH:ko02020]
         04010 MAPK signaling pathway [PATH:ko04010]
         04012 ErbB signaling pathway [PATH:ko04012]
         04310 Wnt signaling pathway [PATH:ko04310]
         04330 Notch signaling pathway [PATH:ko04330]
         04340 Hedgehog signaling pathway [PATH:ko04340]
         04350 TGF-beta signaling pathway [PATH:ko04350]
         04370 VEGF signaling pathway [PATH:ko04370]
         04630 Jak-STAT signaling pathway [PATH:ko04630]
         04020 Calcium signaling pathway [PATH:ko04020]
         04070 Phosphatidylinositol signaling system [PATH:ko04070]
         04150 mTOR signaling pathway [PATH:ko04150]

       01330 Signaling Molecules and Interaction

         04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
         04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
         04512 ECM-receptor interaction [PATH:ko04512]
         04514 Cell adhesion molecules (CAMs) [PATH:ko04514]

     01400 Cellular Processes

       01410 Cell Motility

         02030 Bacterial chemotaxis [PATH:ko02030]
         02040 Flagellar assembly [PATH:ko02040]
         04810 Regulation of actin cytoskeleton [PATH:ko04810]

       01420 Cell Growth and Death

         04410 Cell division
         04420 Sporulation
         04430 Germination
         04110 Cell cycle [PATH:ko04110]
         04111 Cell cycle - yeast [PATH:ko04111]
         04210 Apoptosis [PATH:ko04210]

       01430 Cell Communication

         04510 Focal adhesion [PATH:ko04510]
         04520 Adherens junction [PATH:ko04520]
         04530 Tight junction [PATH:ko04530]
         04540 Gap junction [PATH:ko04540]

       01480 Endocrine System

         04910 Insulin signaling pathway [PATH:ko04910]
         04920 Adipocytokine signaling pathway [PATH:ko04920]
         03320 PPAR signaling pathway [PATH:ko03320]
         04912 GnRH signaling pathway [PATH:ko04912]
         04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
         04916 Melanogenesis [PATH:ko04916]
         04614 Renin - angiotensin system [PATH:ko04614]

       01460 Immune System

         04640 Hematopoietic cell lineage [PATH:ko04640]
         04610 Complement and coagulation cascades [PATH:ko04610]
         04620 Toll-like receptor signaling pathway [PATH:ko04620]
         04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
         04612 Antigen processing and presentation [PATH:ko04612]
         04660 T cell receptor signaling pathway [PATH:ko04660]
         04662 B cell receptor signaling pathway [PATH:ko04662]
         04664 Fc epsilon RI signaling pathway [PATH:ko04664]
         04670 Leukocyte transendothelial migration [PATH:ko04670]

       01470 Nervous System

         04720 Long-term potentiation [PATH:ko04720]
         04730 Long-term depression [PATH:ko04730]

       01475 Sensory System

         04740 Olfactory transduction [PATH:ko04740]
         04742 Taste transduction [PATH:ko04742]

       01440 Development

         04320 Dorso-ventral axis formation [PATH:ko04320]
         04360 Axon guidance [PATH:ko04360]

       01450 Behavior

         04710 Circadian rhythm [PATH:ko04710]

     01500 Human Diseases

       01510 Neurodegenerative Disorders

         05010 Alzheimer's disease [PATH:ko05010]
         05020 Parkinson's disease [PATH:ko05020]
         05030 Amyotrophic lateral sclerosis (ALS) [PATH:ko05030]
         05040 Huntington's disease [PATH:ko05040]
         05050 Dentatorubropallidoluysian atrophy (DRPLA) [PATH:ko05050]
         05060 Prion disease [PATH:ko05060]

       01520 Infectious Diseases

         05110 Cholera [PATH:hsa05110]
         05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
         05130 Pathogenic Escherichia coli infection [PATH:hsa05130]

       01530 Metabolic Disorders

         04940 Type I diabetes mellitus [PATH:ko04940]
         04930 Type II diabetes mellitus [PATH:ko04930]
         04950 Maturity onset diabetes of the young [PATH:ko04950]

       01540 Cancers

         05210 Colorectal cancer [PATH:ko05210]
         05212 Pancreatic cancer [PATH:ko05212]
         05214 Glioma [PATH:ko05214]
         05216 Thyroid Cancer [PATH:ko05216]
         05220 Chronic myeloid leukemia [PATH:ko05220]
         05217 Basal cell carcinoma [PATH:ko05217]
         05218 Melanoma [PATH:ko05218]
         05211 Renal cell carcinoma [PATH:ko05211]
         05215 Prostate cancer [PATH:ko05215]
         05213 Endometrial cancer [PATH:ko05213]
         05222 Small cell lung cancer [PATH:ko05222]
         05223 Non-small cell lung cancer [PATH:ko05223]

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Last updated: June 7, 2007