get.helland.subtypes {consensusOV} | R Documentation

## Get ovarian cancer subtypes as defined by Helland et al., 2011

### Description

Get ovarian cancer subtypes as defined by Helland et al., 2011

### Usage

    get.helland.subtypes(expression.matrix, entrez.ids)

### Arguments

`expression.matrix` | A matrix of gene expression values with rows as genes, columns as samples.
`entrez.ids` | A vector of Entrez Gene IDs, corresponding to the rows of `expression.matrix`

### Value

A list with first value `Helland.subtypes` containing a factor of subtype names; and second value `subtype.scores` containing a matrix of subtype scores

### References

Helland et al. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PloS one (2011).

### Examples

    library(Biobase)
    data(GSE14764.eset)
    expression.matrix <- exprs(GSE14764.eset)
    entrez.ids <- as.character(fData(GSE14764.eset)$EntrezGene.ID)
    get.helland.subtypes(expression.matrix, entrez.ids)

[Package consensusOV version 1.8.1 Index]