defuseTPTN {chimera} | R Documentation

## A function that genererate a list of fSet objects encopassing 60 experimentally validated fusions and 61 false fusions

### Description

The function uses the file defuse_TP_FP.txt located in the examples folder of chimera to generate a list of fSet object encompassing 60 TP fusions and 61 TN fusions extracted from supplementary table 8 of the deFuse paper McPherson et al. (2011) PLoS Comput Biol 7(5): e1001138. The fset object can be used to evaluate the efficacy of filtering approaches available in chimera package.

### Usage

    defuseTPTN()

### Value

An list of fSet objects: Experimentally validated fusions 1-60, fish validated fusions 1-14, false fusions 61-121.

### Author(s)

Raffaele A Calogero

### Examples

    tptn <-defuseTPTN()

[Package chimera version 1.27.1 Index]