OVESEG-package {OVESEG} | R Documentation

## OVESEG: A package for marker gene test.

### Description

Function `OVESEGtest` performs OVESEG-test for expression profiles from multiple groups to detect subtype-specific marker genes. While it may take a long time to execute permutations for p-value estimation, users can apply `OVESEGtstat` to obtain OVESEG-test statistics to rank genes and apply `postProbNull` to obtain each gene's posterior probabilities of component null hypotheses. `nullDistri` estimates probabilities of any one group being upregulated under null hypotheses. `patternDistri` estimates probabilities of all kinds of upregulation patterns among groups.

### References

Chen, L., Herrington, D., Clarke, R., Yu, G., and Wang, Y. (2019). “Data-Driven Robust Detection of Tissue/Cell-Specific Markers.” bioRxiv. https://doi.org/10.1101/517961.

[Package OVESEG version 1.2.0 Index]