hic_example_data {GenomicInteractions} | R Documentation

## Example HiC dataset

### Description

This dataset contains HiC data from Seitan et al. 2013. The data was analysed using HOMER (Heinz et al. 2010) at a resolution of 100kb to find significant interactions. This example dataset has been filtered to retain only interactions on chromosomes 14 and 15 with a FDR < 0.1. The data has also been annotated for overlaps with Refseq promoters. See the HiC analysis vignette (`vignettes(GenomicInteractions)`) for more information on how this dataset was created.

### Usage

    data(hic_example_data)

### Format

A GenomicInteractions object with length 8171.

### Value

GenomicInteractions object

### References

Seitan, V. C. et al. Cohesin-based chromatin interactions enable regulated gene expression within pre-existing architectural compartments. Genome Res. 23, 2066-77 (2013).

Heinz S, Benner C, Spann N, Bertolino E et al. Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities. Mol Cell 2010 May 28;38(4):576-589.

[Package GenomicInteractions version 1.20.3 Index]