cvExpr {CHARGE} | R Documentation

## cvExpr

### Description

Calculates the coefficient of variation for each gene within a defined genomic region.

### Usage

    cvExpr(se, region)

### Arguments

`se` | A SummarizedExperiment containing the normalised gene expression data.
`region` | A GRanges object containing the genomic location of the region of interest. This can either be an entire length or the subset of a chromosome.

### Details

Calculates the coefficient of variation (CV) for each gene with a genomic region of interest. The CV Values can be used to determine which genes are not critical for appropiate clustering and can be filtered out prior to clustering.

### Value

Returns a list containing the CV of each gene and the the quantile threshold of the data.

### Author(s)

Benjamin Mayne

### Examples

    library(GenomicRanges)
    data(datExprs)
    chr21 <- GRanges("21:1-46709983")
    cvExpr.out <- cvExpr(se = datExprs, region = chr21)

[Package CHARGE version 1.6.0 Index]