Package: BioNet
Type: Package
Title: Routines for the functional analysis of biological networks
Version: 1.12.0
Date: 2011-05-03
Author: Marcus Dittrich and Daniela Beisser
Maintainer: Marcus Dittrich
        <marcus.dittrich@biozentrum.uni-wuerzburg.de>
Description: This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.
License: GPL (>= 2)
Depends: R (>= 2.10.0), Biobase, graph, RBGL
Suggests: rgl, impute, DLBCL, genefilter, xtable, ALL, limma,
        hgu95av2.db, XML
Imports: igraph, AnnotationDbi
LazyLoad: yes
URL: http://bionet.bioapps.biozentrum.uni-wuerzburg.de/
biocViews: Microarray, DataImport, GraphsAndNetworks, Visualization,
        Bioinformatics, GeneExpression, DifferentialExpression
Packaged: 2011-11-01 07:30:06 UTC; biocbuild
Built: R 2.14.0; ; 2011-11-01 14:43:20 UTC; unix
