Package: joda
Type: Package
Title: JODA algorithm for quantifying gene deregulation using knowledge
Version: 1.0.0
Date: 2011-04-03
Author: Ewa Szczurek
Description: Package 'joda' implements three steps of an algorithm
        called JODA. The algorithm computes gene deregulation scores.
        For each gene, its deregulation score reflects how strongly an
        effect of a certain regulator's perturbation on this gene
        differs between two different cell populations. The algorithm
        utilizes regulator knockdown expression data as well as
        knowledge about signaling pathways in which the regulators are
        involved (formalized in a simple matrix model).
Reference: Szczurek E, Markowetz F, Gat-Viks I, Biecek P, Tiuryn J,
        Vingron M: Deregulation upon DNA damage revealed by joint
        analysis of context-specific perturbation data.  Submitted.
Maintainer: Ewa Szczurek <szczurek@molgen.mpg.de>
Depends: R (>= 2.0), bgmm, RBGL
biocViews: Microarray, Bioinformatics, Pathways, GraphsAnNetworks,
        Statistics
URL: http://www.bioconductor.org
License: GPL (>= 2)
Packaged: 2011-04-14 10:44:34 UTC; biocbuild
Built: R 2.13.0; ; 2011-04-14 15:22:58 UTC; windows
