Krogan               package:apComplex               R Documentation

_H_i_g_h-_D_e_f_i_n_i_t_i_o_n _M_a_c_r_o_m_o_l_e_c_u_l_a_r _C_o_m_p_o_s_i_t_i_o_n _o_f _Y_e_a_s_t
_R_N_A-_P_r_o_c_e_s_s_i_n_g _C_o_m_p_l_e_x_e_s (_2_0_0_4)

_D_e_s_c_r_i_p_t_i_o_n:

     AP-MS data published by Krogan et al. (2004)

_U_s_a_g_e:

     data(Krogan)

_D_e_t_a_i_l_s:

     'Krogan' is a matrix of the AP-MS data published by Krogan et al
     (2004). The 153 rows correspond to bait proteins and the 485
     columns correspond to proteins found as hits in the AP-MS
     experiment and are named accordingly. The first 153 column names
     are the same as the 153 row names; bait proteins can also be found
     as hits by other baits, hence their inclusion as columns in
     'Krogan'.  An entry of "1" in the ith row and jth column of
     'Krogan' indicates that bait protein i found protein j as a hit. 
     All other entries are "0".  There are a total of 1132 "1" entries
     in the matrix, corresponding to the 1132 comemberships detected in
     the experiment.

     These data are available at
     http://www.molecule.org/cgi/content/full/13/2/225/DC1/.

_S_o_u_r_c_e:

     Krogan, et al.  High-Definition Macromolecular Composition of
     Yeast RNA-Processing Complexes; Molecular Cell, Vol 13, 225-239,
     30 January 2004.

_R_e_f_e_r_e_n_c_e_s:

     Scholtens D and Gentleman R.  Making sense of high-throughput
     protein-protein interaction data.  Statistical Applications in
     Genetics and Molecular Biology 3, Article 39 (2004).

     Scholtens D, Vidal M, and Gentleman R.  Local modeling of global
     interactome networks.  Bioinformatics 21, 3548-3557 (2005).

_S_e_e _A_l_s_o:

     'MBMEcKrogan'

_E_x_a_m_p_l_e_s:

     data(Krogan)

